Early mortality and functional outcome after acute stroke in Uganda: prospective study with 30 day follow-up

نویسندگان

  • Jane Nakibuuka
  • Martha Sajatovic
  • Joaniter Nankabirwa
  • Charles Ssendikadiwa
  • Anthony J. Furlan
  • Elly Katabira
  • James Kayima
  • Nelson Kalema
  • Jayne Byakika-Tusiime
  • Edward Ddumba
چکیده

Identification of early outcomes post stroke and their predictors is important in stroke management strategies. We prospectively analysed 30-day outcomes (mortality and functional ability) after stroke and their predictors among patients admitted within 7 days post event to a national referral hospital in Uganda. This was a prospective study of acute stroke patients consecutively enrolled between February and July 2014. Social demographics, clinical, laboratory, imaging characteristics, outcomes (all through 30 days), time of death were assessed using standardised questionnaires. Multiple regression was used to analyse the independent influence of factors on outcomes. Of 127 patients, 88 (69.3 %) had ischemic stroke and 39 (30.7 %) had hemorrhagic stroke. Eight (6.3 %) died within 7 days, 34 (26.8 %) died within 30 days, with 2/3 of deaths occurring in hospital. Two were lost to follow up. Of 91 survivors, 49 (53.9 %) had satisfactory outcome, 42 (46.1 %) had poor functional outcome. At multivariate analysis, independent predictors of mortality at 30 days were unconsciousness (GCS <9), severe stroke at admission and elevated fasting blood sugar. None of the patients with functional independence (Barthel index ≥60) at admission died within 30 days. Inverse independent predictors of satisfactory outcome at 30 days were older age, history of hypertension and severe stroke at admission. Acute stroke patients in Uganda still have high rates of early mortality and poor functional outcomes. Independent predictors of mortality and poor functional outcome were severe stroke at admission, unconsciousness, high fasting blood sugar, old age and history of hypertension.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

EVALUATION OF OUTCOME OF CONSERVATIVE TREATMENT IN PATIENTS WITH MASSIVE ISCHEMIC STROKE WHO HAVE NOT UNDERGONE CRANIECTOMY SURGERY

Background & Aims: Decompressive Craniectomy (DC) is recommended for patients with extensive cerebral infarction. At this study, we aimed to assess the mortality and 3-month outcome of these patients who are not going under DC. Material & Methods: In this prospective descriptive study, all patients referred to Imam Reza Hospital in Urmia, Iran, from 2017-2019 with extensive ischemic stroke wit...

متن کامل

Ability of serum C-reactive protein and white blood cell cout in predicting acute schemic stroke. A short -term follow-up study

Background: Stroke is one of the leading causes of mortality and long-term morbidity. The aim of the present study was to determine the ability of baseline serum C-reactive protein (CRP) and white blood cell count (WBC) values in predicting the outcome of acute ischemic stroke (AIS). Methods: This study consisted of patients with first AIS referred to Poursina Hospital, Rasht, Iran. Severity...

متن کامل

Plasma D-Dimer Predicts Short-Term Poor Outcome after Acute Ischemic Stroke

OBJECTIVE Haemostatic biomarkers associated with poor outcome in acute ischemic stroke (AIS). The objective of the study was to evaluate the predictive value of plasma D-dimer (D-D) on functional outcome at 90-day follow-up from stroke onset. METHODS We conducted a prospective, observational cohort study in the emergency department and enrolled 220 patients with AIS. Plasma D-D concentrations...

متن کامل

Opium dependency and in-hospital outcome of acute myocardial infarction

  Background :Impact of substance abuse on outcome of hospitalized patients with acute myocardial infarction (MI) is a frequent question. Available studies show disagreements over its impact, thus we performed this study to find a clear answer.   Methods : In a cross sectional study, 304 patients (include 152 consecutive opium dependents and equal number of independents) with acute MI admitted ...

متن کامل

Association of high waist-to-height ratio with functional outcomes in patients with acute ischemic stroke

The aim of our study was to investigate the relationship between the waist-to-height ratio (WHR) and all-cause mortality and functional outcomes after acute ischemic stroke in a prospective cohort study.A total of 2076 patients (36.66% females) with ischemic stroke were analyzed from ACROSS-China, which is a nationwide, prospective, hospital-based stroke registry aimed to detect the glucose abn...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2015